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| Product Name | Anti-RAB21 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAICC/IFIHC |
| IHC:1:200-1:2000 ICC/IF:1:100-1:500 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | RAB21 |
|---|---|
| Gene Synonyms | |
| Gene Full Name | RAB21, member RAS oncogene family |
| Gene Summary | This gene belongs to the Rab family of monomeric GTPases, which are involved in the control of cellular membrane traffic. The encoded protein plays a role in the targeted trafficking of integrins via its association with integrin alpha tails. As a consequence, the encoded protein is involved in the regulation of cell adhesion ａnd migration. Expression of this gene is associated with a poor prognosis for glioma patients. This gene is downregulated by the tumor suppressor miR-200b, ａnd miRNA-200b is itself downregulated in glioma tissues. [provided by RefSeq, Nov 2015] More |
| Molecular Weight(MW) | 24KD |
| Cellular Localization | Cell projection, Cylasmic vesicle, Endoplasmic reticulum, Endosome, Golgi apparatus, Membrane |
Immunohistochemical analysis of paraffin-em
Immunohistochemical analysis of paraffin-em
Immunofluorescence analysis of A549 cells using RAB21 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
| Application Notes | IHC:1:200-1:2000 ICC/IF:1:100-1:500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
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