標題PSMB8 antibody Catalog Number：OM272726

提供者：上海篤瑪生物科技有限公司發布時間：2024/9/27 閱讀次數：51次 >>進入該公司展臺

Product Name	PSMB8 antibody
Antibody Type	Primary Antibodies
Product description	Mouse Monoclonal Antibody [1A5] to PSMB8The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits ａnd 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration ａnd cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon ａnd this gene product replaces catalytic subunit 3 (proteasome beta 5 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. Two alternative t More
Immunogen	The immunogen corresponding to human PSMB8 expressed in E. Coli.

Gene Synonyms	RING10 D6S216 LMP7 NKJO PSMB5I ALDD JMP D6S216E More
Target	PSMB8
Molecular Weight(MW)	30 kDa (note)

Application

ELISA analysis of control antigen ａnd antigen using PSMB8 antibody [1A5].
Application

ICC/IF analysis of HeLa cells using PSMB8 antibody [1A5] (green), Alexa Fluor-555 phalloidin (red) ａnd DRAQ5 fluorescent DNA dye (blue).
Application

IHC-P analysis of colon tissues using PSMB8 antibody [1A5].
Application

IHC-P analysis of intima cancer tissues using PSMB8 antibody [1A5].
Application

WB analysis of (1) HeLa, (2) MCF-7, (3) A431, (4) RAJI, (5) MOTL4 ａnd (6) PC-12 lysates using PSMB8 antibody [1A5].
Application

WB analysis of human PSMB8 (a.a. 1-272) recombinant protein using PSMB8 antibody [1A5].