標題FIBG Antibody Catalog Number：OM278858

提供者：上海篤瑪生物科技有限公司發布時間：2024/9/19 閱讀次數：44次 >>進入該公司展臺

Product Name	FIBG Antibody
Antibody Type	Primary Antibodies
Product description	FIBG is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen ａnd fibrin regulate cell adhesion ａnd spreading, display vasoconstrictor ａnd chemotactic activities, ａnd are mitogens for several cell types. Mutations in its gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia ａnd thrombophilia.1) Nowak-Gottl,U., Blood 114 (9), 1947-1953 (2009) More
Immunogen	This FIBG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 420-449 amino acids from the C-terminal region of human FIBG.

Clonality	Polyclonal
Isotype	Ig
Host Species	Rabbit
Tested Applications	IFIHC-PWB
	For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50 For IF starting dilution is: 1:10~50:
Species Reactivity	Human
Concentration	1 mg/ml

Entrez Gene	2266
Protein Accession	P02679

Application

Confocal immunofluorescent analysis of FIBG Antibody with MDA-MB231 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue).
Application

FIBG Antibody IHC analysis in formalin fixed ａnd paraffin embedded human skeletal muscle tissue followed by peroxidase conjugation of the secondary antibody ａnd DAB staining.
Application

Western blot analysis of FIBG Antibody in NCI-H460 cell line lysates (35ug/lane)
Application

Western Blot at 1:4000 dilution + A431 whole cell lysate Lysates/proteins at 20 ug per lane.

Application Notes	For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50 For IF starting dilution is: 1:10~50:

Form	Liquid
Storage Instructions	Store at 4˚C for three months ａnd -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.

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