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| Product Name | WHSC2 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB~~1:100~500: | |
| Species Reactivity | Human |
| Concentration | 1 mg/ml |
| Purification |
| Gene Synonyms | |
|---|---|
| Alternative Names | More |
| Molecular Weight(MW) | 57277 Da |
| Function | Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex ａnd causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. Probably required to interact with the RNA polymerase II complex More |
| Tissue Specificity | Ubiquitous. Expressed in heart, brain, placenta, liver, skeletal muscle, kidney ａnd pancreas. Expressed at lower level in adult lung. Expressed in fetal brain, lung, liver ａnd kidney |
| Cellular Localization | Nucleus. |
| Entrez Gene | 7469 |
|---|---|
| Nucleotide Accession | NP_005654.3 |
WHSC2 Antibody (Center) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the WHSC2 antibody detected the WHSC2 protein (arrow).
| Application Notes | WB~~1:100~500: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot ａnd store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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