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              您的位置:首頁 > 技術文獻 > 產品說明 > Anti-WHSC2 antibody Catalog Number:OM642659

              標題Anti-WHSC2 antibody Catalog Number:OM642659

                 

              提供者:上海篤瑪生物科技有限公司    發布時間:2024/9/2   閱讀次數:25次 >>進入該公司展臺
               

              Product Profile

              Product Name Anti-WHSC2 antibody
              Antibody Type Primary Antibodies
              Immunogen
              Polypeptide

              Key Feature

              Clonality Polyclonal
              Isotype IgG
              Host Species Rabbit
              Tested Applications

              ELISAIHCWB

               
              WB:1:200-1:2000
              IHC:1:200-1:2000
              Species Reactivity

              HumanMouseRat

              Concentration 1mg/ml
              Purification Protein A

              Target Information

              Gene Symbol NELFA
              Gene Synonyms
              WHSC2
              NELF-A
              P/OKcl.15
              Gene Full Name negative elongation factor complex member A
              Gene Summary
              This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation. [provided by RefSeq, Jul 2008]
              More 
              Molecular Weight(MW) 57KD
              Cellular Localization Nucleus

              Application

              • WB

                Western blot analysis using WHSC2 antibody against A549(1) cell lysate.

              • IHC

                Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using WHSC2 antibody with DAB staining.

              • IHC

                Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using WHSC2 antibody with DAB staining.

              Application Notes
              WB:1:200-1:2000
              IHC:1:200-1:2000

              Additional Information

              Form Liquid
              Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
              Storage Buffer Purified antibody in PBS with 0.05% sodium azide.

              關鍵詞:Product  Profile  Product  NameAnti-WHSC2  antibody  Antibody  TypePrimary  Antibodies  Immunogen  Polype  

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