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| Product Name | Anti-TGF beta1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIHCWB |
| WB:1:200-1:2000 IHC:1:200-1:1000 | |
| Species Reactivity | GoatHumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | TGFB1 |
|---|---|
| Gene Synonyms | More |
| Gene Full Name | transforming growth factor beta 1 |
| Gene Summary | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment ａnd activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) ａnd a mature peptide, ａnd is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, ａnd a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation, differentiation ａnd growth, ａnd can modulate expression ａnd activation of other growth factors including interferon gamma ａnd tumor necrosis factor alpha. This gene is frequently upregulated in tumor cells, ａnd mutations in this gene result in Camurati-Engelmann disease. [provided by RefSeq, Aug 2016] More |
| Molecular Weight(MW) | 44 kDa（Observed:53 kDa） |
| Cellular Localization | Extracellular region or secreted |
Western blot analysis using TGF beta1 antibody against Hela (1), A431 (2) cell lysate.
Immunohistochemical analysis of paraffin-em
| Application Notes | WB:1:200-1:2000 IHC:1:200-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide |
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