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              您的位置:易推廣 > 化工原料 > 化學試劑 > 分析試劑 > 武漢艾美捷科技有限公司 > 產品展示 > 生物試劑 > 中英文說明丨艾美捷血管緊張素ⅡELISA試劑盒方案

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              中英文說明丨艾美捷血管緊張素ⅡELISA試劑盒方案

              點擊次數:0發布時間:2023/1/17 16:55:22

              中英文說明丨艾美捷血管緊張素ⅡELISA試劑盒方案

              更新日期:2023/1/17 16:55:22

              所 在 地:中國大陸

              產品型號:

              簡單介紹:血管緊張素Ⅱ ELISA試劑盒:高靈敏度ELISA,檢測量低至4.6pg/ml

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              詳細內容

               Angiotensins are small peptides derived from angiotensinogen. Several of the known angiotensins are established endocrine effectors in the regulation of blood pressure, but they are also known to have other functions locally, in several organs and tissues (paracrine) and at the cellular level (autocrine / intracrine). Angiotensin I (DRVYIHPFHL) has no known effector function but it is an immediate precursor of Angiotensin II (DRVYIHPF). Angiotensin II binds AT1 receptors, which promote vasoconstriction, sodium retention, release of aldosterone, release of Arg-vasopressin, cell proliferation, inflammation, fibrosis, anxiety, and cardiac hypertrophy. Angiotensin A (ARVYIHPF), and Angiotensin III (RVYIHPF), also bind AT1 receptors. Angiotensin (1-7) (DRVYIHP) binds a different receptor called MAS-1 which has opposite effects (vasodilation, natriuresis, antiproliferation, NO release, PGE release, and apoptosis). Angiotensin IV (VYIHPF) binds yet another receptor called AT4 (IRAP), which promotes increase of blood flow, angiogenesis, and natriuresis, and which has also been implicated in memory formation and in the pathogenesis of Alzheimers disease. The peptide LVV-hemorphin-7 (LVVYPWTQRF), which is not an angiotensin, also binds the AT4 receptor. There are other angiotensin peptides that have been identified, including Ang (1-9) (DRVYIHPFH), Ang (1-12) (DRVYIHPFHLVI), Ang V(3-7) (VYIHP), as well as several other shorter peptides that have undetermined functions.

              Sensitivity: 4.6 pg/ml (range 3.9-10,000 pg/ml)

              Assay Time: 3.5 hours

              Applications: ELISA, Colorimetric detection

              Application Notes: For the quantitative determination of species independent Angiotensin II in plasma and serum samples.

              Wavelength: 450 nm

              Species reactivity: Species independent

              Crossreactivity: Angiotensin II (100%), Angiotensin A (100%), Angiotensin III (100%), Angiotensin IV (100%), Angiotensin I (0.319%), Angiotensin (1-9) (0.103%), LVV-hemorphin 7 (0.067%), Angiotensin (1-7) (0.053%), Bradykinin (0.022%)

              Quantity: 1 x 96-well plate

              Use/Stability: Store all components at +4ºC, except Standard at -20ºC.

              Shipping: Shipped on Blue Ice

              Contents: Microtiter Plate, Conjugate, Antibody, Assay Buffer 16, Wash Buffer Concentrate, Standard, TMB Substrate, S Solution 2, Streptavidin-HRP

               

              ADI-900-204血管緊張素ⅡELISA試劑盒:高靈敏度ELISA,檢測量低至4.6pg/ml。

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              艾美捷ADI-900-204 血管緊張素ⅡELISA試劑盒化學性質:

              靈敏度:4.6 pg/ml(范圍3.9-10000 pg/ml

              化驗時間:3.5小時

              應用:ELISA,比色檢測

              應用說明:用于定量測定血漿和血清樣品中的種類無關的血管緊張素II。

              波長:450 nm

              物種反應性:物種無關

              交叉反應性:血管緊張素II100%),血管緊張素A100%)、血管緊張素III100%)和血管緊張素IV100%

              數量:1 x 96孔板

              使用/穩定性:將所有組件儲存在+4ºC,標準組件除外,儲存在-20ºC。

              運輸:藍冰運輸

              內容:微量滴定板、綴合物、抗體、測定緩沖液16、洗滌緩沖液濃縮液、標準品、TMB底物、停止溶液2、鏈霉親和素HRP

               

              血管緊張素ⅡELISA試劑盒文獻參考:

              Hypertension enhances advanced atherosclerosis and induces cardiac death in Watanabe heritable hyperlipidemic rabbits: B. Ning, et al.; Am. J. Pathol. 188, 2936 (2018);

              Post-translational modifications of eNOS augment nitric oxide availability and facilitates hypoxia adaptation in Ladakhi women: Pooja, et al.; Nitric Oxide 78, 103 (2018), Application(s): ELISA using human plasma;

              Prorenin independently causes hypertension and renal and cardiac fibrosis in cyp1a1-prorenin transgenic rats: G. Zhou, et al.; Clin. Sci. (Lond.) 132, 1345 (2018);

              12-Lipoxygenase Inhibition on Microalbuminuria in Type-1 and Type-2 Diabetes Is Associated with Changes of Glomerular Angiotensin II Type 1 Receptor Related to Insulin Resistance: H.Z. Xu, et al.; Int. J. Mol. Sci. 17, E684 (2016), Application(s): Measurement of Angiotensin levels in rat;

               

              來源:https://www.amyjet.com/products/ADI-900-204.shtml

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