產品展示
Recombinant Murine IL-1a廠家直銷
點擊次數：28發布時間：2016/1/26 13:26:46
更新日期：2016/1/26 13:26:46
所 在 地：中國大陸
產品型號：211-11A
優質供應
詳細內容
產品編號:
211-11A
別名:
Hematopoietin-1, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)
描述:
IL-1α is a non-secreted, proinflammatory cytokine produced in a variety of cells, including monocytes, tissue macrophages, keratinocytes ａnd other epithelial cells. Both IL-1α ａnd IL-1β bind to the same receptor ａnd have similar, if not identical, biological properties. These cytokines have a broad range of activities including the stimulation of thymocyte proliferation by inducing IL-2 release, B-cell maturation ａnd proliferation, mitogenic FGF-like activity, ａnd the release of prostaglandin ａnd collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant Murine IL-1α is a 17.9 kDa protein containing 156 amino acid residues.
氨基酸序列:
SAPYTYQSDL RYKLMKLVRQ KFVMNDSLNQ TIYQDVDKHY LSTTWLNDLQ QEVKFDMYAY SSGGDDSKYP VTLKISDSQL FVSAQGEDQP VLLKELPETP KLITGSETDL IFFWKSINSK NYFTSAAYPE LFIATKEQSR VHLARGLPSM TDFQIS
來源:
E.coli
純度:
Greater than 98% by SDS-PAGE gel ａnd HPLC analyses.
生物活性:
The ED50 as determined by the dose-dependent stimulation of murine D10S cells is < 0.002 ng/ml, corresponding to a specific activity of > 5 x 108units/mg.
交叉反應:
Mouse, Human, Rat + Chicken
研究領域:
原產國:
USA
僅用于研究。不適用于診斷或治療。
