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              技術文章

              LIMS1 antibody Catalog Number:OM261584

              點擊次數:35 發布時間:2024/9/29 14:29:34
               

              Product Profile

              Product Name LIMS1 antibody
              Antibody Type Primary Antibodies
              Product description
              Rabbit Polyclonal antibody to Pinch 1 (LIM and senescent cell antigen-like domains 1)The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. [provided by RefSeq]
              More 
              Immunogen
              Recombinant protein encompassing a sequence within the center region of human LIMS1. The exact sequence is proprietary.

              Key Feature

              Clonality Polyclonal
              Isotype IgG
              Host Species Rabbit
              Tested Applications

              IHC-PWB

               
              *Optimal dilutions/concentrations should be determined by the researcher. :
              Species Reactivity

              Human

              Predicted Reactivity Mouse, Rat, Zebrafish, Xenopus laevis, Pig, Chicken, BovineMouse (99%), Rat (99%), Zebrafish (95%), Xenopus laevis (97%), Pig (98%), Chicken (95%), Bovine (99%)
              Concentration 1 mg/ml
              Purification Affinity purified

              Target Information

              Gene Synonyms
              PINCH antibody
              PINCH1 antibody
              LIMS1 antibody
              renal carcinoma antigen NY-REN-48 antibody
              particularly interesting new Cys-His protein 1 antibody
              LIM and senescent cell antigen-like-containing domain protein 1 antibody
              LIM and senescent cell antigen-l
              More 
              Molecular Weight(MW) 37 kDa (note) (7)

              Application

              • Application

                Immunohistochemical analysis of paraffin-embedded BT474 xenograft, using Pinch 1 antibody at 1:100 dilution.

              • Application

                Sample (30 ug of whole cell lysate) A: Hela 10% SDS PAGE diluted at 1:1000

              Positive Control A549 , HeLa , HCT116
              Application Notes
              *Optimal dilutions/concentrations should be determined by the researcher. :

              Additional Information

              Form Liquid
              Storage Instructions Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
              Storage Buffer 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

              原創作者:上海篤瑪生物科技有限公司

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