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技術文章
Anti-PINCH antibody Catalog Number：OM642068
點擊次數：30 發布時間：2024/9/29 14:09:16
Product Profile
| Product Name | Anti-PINCH antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Recombinent Proteins |
Key Feature
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Mouse |
| Tested Applications | ELISAICC/IFIHC |
| IHC:1:200-1:1000 ICC/IF:1:100-1:500 | |
| Species Reactivity | HumanRabbit |
| Concentration | 1 mg/ml |
| Purification | Protein A |
Target Information
| Gene Symbol | LIMS1 |
|---|---|
| Gene Synonyms | |
| Gene Full Name | LIM zinc finger domain containing 1 |
| Gene Summary | The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010] More |
| Source | Mouse |
| Cellular Localization | Cell junction, Cell membrane, Membrane |
Application
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IHC
Immunohistochemical analysis of paraffin-em
bedded lung breast tissues using PINCH antibody with DAB staining. -
ICC/IF
Immunofluorescence analysis of A549cells using PINCH antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
| Application Notes | IHC:1:200-1:1000 ICC/IF:1:100-1:500 |
|---|
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
原創作者：上海篤瑪生物科技有限公司
