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              技術文章

              MCM7 antibody Catalog Number:OM262670

              點擊次數:41 發布時間:2024/9/27 15:00:59
               

              Product Profile

              Product Name MCM7 antibody
              Antibody Type Primary Antibodies
              Product description
              Rabbit Polyclonal antibody to MCM7The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
              More 
              Immunogen
              Recombinant protein of human MCM7

              Key Feature

              Clonality Polyclonal
              Isotype IgG
              Host Species Rabbit
              Tested Applications

              ICC/IFIHC-PWB

               
              WB: 1:500 - 1:2000. IHC: 1:50 - 1:200. IF: 1:50 - 1:200:
              Species Reactivity

              HumanMouseRat

              Concentration 1 mg/ml
              Purification Affinity purified

              Target Information

              Gene Synonyms
              minichromosome maintenance complex component 7
              P1.1-MCM3
              P1CDC47
              PNAS146
              P85MCM
              CDC47
              MCM2
              More 
              Target MCM7
              Molecular Weight(MW) 81 kDa (note)

              Application

              • Application

                WB analysis of extracts from various cells using MCM7 antibody.

              • Application

                IHC-P analysis of human breast cancer using MCM7 antibody at a dilution of 1:200.

              • Application

                IHC-P analysis of human esophageal cancer using MCM7 antibody at a dilution of 1:200.

              • Application

                IHC-P analysis of human rectal cancer using MCM7 antibody at a dilution of 1:200.

              • Application

                IHC-P analysis of rat brain using MCM7 antibody at a dilution of 1:200.

              • Application

                ICC/IF analysis of HeLa cells using MCM7 antibody (green) and DAPI (blue).

              Application Notes
              WB: 1:500 - 1:2000. IHC: 1:50 - 1:200. IF: 1:50 - 1:200:

              Additional Information

              Form Liquid
              Storage Instructions Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles.
              Storage Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

              原創作者:上海篤瑪生物科技有限公司

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