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              技術文章

              MCM7 antibody Catalog Number:OM262672

              點擊次數:50 發布時間:2024/9/27 14:59:40
               

              Product Profile

              Product Name MCM7 antibody
              Antibody Type Primary Antibodies
              Product description
              Mouse monoclonal [47DC141] to MCM7hCDC47 is a human member of the MCM family, which allows DNA to replicate once per cell cycle. In quiescent cells, human MCM7 (hMCM7) mRNA is almost undetectable. Stimulation of cells to enter the cell cycle results in induction of hMCM7 expression. The hCDC47 protein expression and localization is found in nuclei of the proliferative components of normal lymph nodes, bone marrow, epidermis and mucosa. Malignant tumors from several organs contained more nuclearhCDC47 positive cells than their normal counterparts. These results indicate that hCDC47 may play a role in normal and neoplastic cell growth in vivo.
              More 
              Immunogen
              Full length recombinant human MCM7

              Key Feature

              Clonality Monoclonal
              Isotype IgG1
              Clone Number 47DC141
              Host Species Mouse
              Tested Applications

              ICC/IFIHC-PIPWB

               
              ICC/IF:1:20~1:100
              IHC-p:1:10~1:50
              WB:1:100~1:200
              IP:1:20~1:100
              More 
              Species Reactivity

              HumanMouseDogRatXenopus

              Concentration 0.2 mg/ml
              Purification Affinity purified

              Target Information

              Gene Synonyms
              CDC47
              MCM2
              P1.1-MCM3
              P1CDC47
              P85MCM
              PNAS146
              P1.1 MCM3
              P1.1MCM3
              More 
              Target MCM7
              Cellular Localization Nuclear .

              Application

              • Application

                Formalin fixed paraffin embedded human tonsil stained with MCM7, using ABC and DAB chromagen.

              • Application

                Formalin-fixed, paraffin-embedded human tonsil stained with using peroxidase-conjugate and DAB chromogen. Note nuclear staining of proliferating cells.

              Positive Control Breast carcinoma
              Application Notes
              ICC/IF:1:20~1:100
              IHC-p:1:10~1:50
              WB:1:100~1:200
              IP:1:20~1:100
              More 

              Additional Information

              Form Liquid
              Storage Instructions Keep as concentrated solution, aliquot and store at 4°C. Do not freeze.
              Storage Buffer PBS, pH7.4 containg 0.2% BSA and 0.09% sodium azide

              原創作者:上海篤瑪生物科技有限公司

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