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              技術文章

              MCM2 Antibody Catalog Number:OM284351

              點擊次數:36 發布時間:2024/9/27 14:30:09
               

              Product Profile

              Product Name MCM2 Antibody
              Antibody Type Primary Antibodies
              Product description
              MCM2, also called DNA replication licensing factor MCM2, Minichromosome maintenance protein 2 homolog or Nuclear Protein BM28) is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by protein kinases CDC2 and CDC7. Double serines at positions 26 and 27 are conserved in rat and mouse. High homology >88% to similar proteins from several other species. Expected broad reactivity to various lysates.
              More 
              Immunogen
              MCM2 antibody was raised against amino acids 21 - 31 of MCM2 (Human).

              Key Feature

              Clonality Polyclonal
              Host Species Rabbit
              Tested Applications

              ELISAIFIHCWB

               
              MCM2 antibody can be used in Western Blot, and immunohistochemistry starting at 10 μg/mL.:
              Species Reactivity

              HumanMouseRatYeast

              Concentration 1 mg/ml
              Purification Affinity purified

              Target Information

              Gene Symbol MCM2
              Alternative Names
              MCM2
              BM28
              Cell devision cycle-like 1
              D3S3194
              Cdc19
              Cyclin-like 1
              KIAA0030
              Nuclear protein BM28
              CDCL1
              MITOTIN
              More 

              Database Links

              Entrez Gene 4171
              Protein Accession P49736

              Application

              • Application

                Immunohistochemistry staining of MCM2 in skin tissue using MCM2 Antibody.

              Application Notes
              MCM2 antibody can be used in Western Blot, and immunohistochemistry starting at 10 μg/mL.:

              Additional Information

              Form Liquid
              Storage Instructions Aliquot and store MCM2 antibody at -20 ˚C. As with all antibodies avoid freeze/thaw cycles.
              Storage Buffer 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.

              原創作者:上海篤瑪生物科技有限公司

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