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技術文章
Rabbit anti-G6PD polyclonal antibody - middle region Catalog Number：OM117661
點擊次數：82 發布時間：2024/9/25 15:17:45
Product Profile
| Product Name | Rabbit anti-G6PD polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | The immunogen for anti-G6PD antibody: synthetic peptide directed towards the middle region of human G6PD |
Key Feature
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. | |
| Species Reactivity | BovineDogGuinea PigHorseHumanMouseRabbitRatSheep |
| Concentration | 1 mg/ml |
| Purification | Affinity purified |
Target Information
| Gene Symbol | G6PD |
|---|---|
| Gene Synonyms | |
| Gene Full Name | Glucose-6-phosphate dehydrogenase |
| Gene Summary | G6PD is a glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents ａnd in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity ａnd associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents ａnd in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity ａnd associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. More |
| Alternative Names | |
| Molecular Weight(MW) | 57kDa |
| Sequence | 515 amino acids |
Database Links
| Entrez Gene | 2539 |
|---|---|
| SwissProt ID | P11413 |
| Protein Accession | NP_000393 |
Application
-
Western blot
Host: Rabbit
Target Name: NSUN6
Sample Tissue: Human Fetal Lung
Antibody Dilution: 1.0ug/ml -
Western blot
0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: MCF7 cell lysate
| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot ａnd store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide ａnd 50% glycerol. |
原創作者：上海篤瑪生物科技有限公司
