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              技術文章

              Myelin Basic Protein Antibody, Monoclonal Catalog Number:OM285643

              點擊次數:43 發布時間:2024/9/25 14:59:04
               

              Product Profile

              Product Name Myelin Basic Protein Antibody, Monoclonal
              Antibody Type Primary Antibodies
              Product description
              Suitable for use in ELISA, Western Blot, Immunohistochemistry and quantification of myelin basic protein. Other applications have not been tested. Recognizes residues 130-136 in human myelin basic protein (21.5kD and 18.5kD molecular forms). Species Crossreactivity: Primate, rabbit, sheep, goat, rat and mouse. The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) found in bone marrow and the immune system may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells.
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              Immunogen
              Myelin Basic Protein monoclonal antibody was raised against amino acids 130 - 136 of Myelin Basic Protein (Human).

              Key Feature

              Clonality Monoclonal
              Isotype IgG2b
              Host Species Mouse
              Tested Applications

              ELISAIHCWB

               
              Myelin Basic Protein antibody can be used in immunocytochemistry starting at 10 μg/mL, immunohistochemistry starting at 10 μg/mL, and flow cytometry.:
              Species Reactivity

              GoatHumanMousePrimateRabbitRatSheep

              Concentration 1 mg/ml
              Purification Protein G

              Target Information

              Gene Symbol MBP
              Alternative Names
              MBP
              Myelin A1 protein
              Myelin basic protein

              Database Links

              Entrez Gene 4155
              Protein Accession P02686

              Application

              • Application

                Immunohistochemistry staining of Myelin Basic Protein in brain, oligodendrocytes tissue using Myelin Basic Protein Monoclonal Antibody.

              Application Notes
              Myelin Basic Protein antibody can be used in immunocytochemistry starting at 10 μg/mL, immunohistochemistry starting at 10 μg/mL, and flow cytometry.:

              Additional Information

              Form Liquid
              Storage Instructions Myelin Basic Protein antibody should be stored at -20 ˚C. As with all antibodies avoid freeze/thaw cycles.
              Storage Buffer PBS, pH 7.4, contains no preservative.
               

              原創作者:上海篤瑪生物科技有限公司

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