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              技術文章

              NQO1 antibody Catalog Number:OM265887

              點擊次數:143 發布時間:2024/9/24 15:08:07
               

              Product Profile

              Product Name NQO1 antibody
              Antibody Type Primary Antibodies
              Product description
              Rabbit Polyclonal antibody to NQO1 (NAD(P)H dehydrogenase, qui 1)This gene is a member of the NAD(P)H dehydrogenase (qui) family and encodes a cylasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quis to hydroquis. This protein's enzymatic activity prevents the one electron reduction of quis that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]
              More 
              Immunogen
              Recombinant protein encompassing a sequence within the center region of human NQO1. The exact sequence is proprietary.

              Key Feature

              Clonality Polyclonal
              Isotype IgG
              Host Species Rabbit
              Tested Applications

              IHC-PWB

               
              *Optimal dilutions/concentrations should be determined by the researcher. :
              Species Reactivity

              HumanMouse

              Predicted Reactivity Rat, Pig, Rhesus Monkey, Bovine, Guinea pigRat (83%), Pig (92%), Rhesus Monkey (98%), Bovine (92%), Guinea pig (86%)
              Concentration 1 mg/ml
              Purification Affinity purified

              Target Information

              Gene Synonyms
              DHQU antibody
              DIA4 antibody
              DTD antibody
              NMOR1 antibody
              NMORI antibody
              QR1 antibody
              NQO1 antibody
              phylloqui reductase antibody
              dioxin-inducible 1 antibody
              azoreductase antibody
              NAD(P)H:Qui acceptor oxidoreductase type 1 antibody
              qui
              More 
              Molecular Weight(MW) 31 kDa (note) (2)
              Cellular Localization Cylasm

              Application

              • Application

                Immunohistochemical analysis of paraffin-embedded A549 xenograft, using NQO1 antibody at 1:100 dilution.

              • Application

                NQO1 antibody detects NQO1 protein by Western blot analysis. A. 50 µg mouse heart lysate/extract 12 % SDS-PAGE NQO1 antibody dilution: 1:500

              • Application

                Sample (30 ug of whole cell lysate) A: Hela B: Hep G2 12% SDS PAGE diluted at 1:1000

              Positive Control HeLa , HepG2 , mouse heart
              Application Notes
              *Optimal dilutions/concentrations should be determined by the researcher. :

              Additional Information

              Form Liquid
              Storage Instructions Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
              Storage Buffer 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

              原創作者:上海篤瑪生物科技有限公司

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