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              技術文章

              DLK1 antibody Catalog Number:OM250156

              點擊次數:34 發布時間:2024/9/23 15:04:18
                

              Product Profile

              Product Name DLK1 antibody
              Antibody Type Primary Antibodies
              Product description
              Mouse Monoclonal Antibody [3A10] to DLK1This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass. [provided by RefSeq, Mar 2010]
              More 
              Immunogen
              The immunogen corresponding to human DLK1 expressed in E. Coli.

              Key Feature

              Clonality Monoclonal
              Isotype IgG1
              Clone Number 3A10
              Host Species Mouse
              Tested Applications

              ELISAFACSICC/IFWB

               
              ELISA: 1/10000.:
              Species Reactivity

              Human

              Concentration 1 mg/ml
              Purification  

              Target Information

              Gene Synonyms
              DLK-1
              DELTA1
              ZOG
              PREF1
              PG2
              FA1
              DLK
              PREF-1
              More 
              Target DLK1
              Molecular Weight(MW) 41 kDa (note)

              Application

              • Application

                ELISA analysis of control antigen and antigen using DLK1 antibody [3A10].

              • Application

                WB analysis of human DLK1 (a.a. 174-349) recombinant protein using DLK1 antibody [3A10].

              • Application

                ICC/IF analysis of U251 cells using DLK1 antibody [3A10] (green), Alexa Fluor-555 phalloidin (red) and DRAQ5 fluorescent DNA dye (blue).

              • Application

                FACS analysis of NIH3T3 cells using DLK1 antibody [3A10] (green) or a negative control (red).

              Application Notes
              ELISA: 1/10000.:

              Additional Information

              Form Liquid
              Storage Instructions 4°C; -20°C for long term storage
              Storage Buffer Ascitic fluid containing 0.03% sodium azide.
               

              原創作者:上海篤瑪生物科技有限公司

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