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              • 注冊資金:人民幣萬

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              聯系人:楊燕燕

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              技術文章

              FGG [C7-H9] Catalog Number:OM627729

              點擊次數:30 發布時間:2024/9/19 11:54:39
               

              Product Profile

              Product Name FGG [C7-H9]
              Antibody Type Primary Antibodies
              Product description
              The plasma glycoprotein Fibrinogen is synthesized in the liver and comprises three structurally different subunits: a, b and g. Fibrinogen is important in platelet aggregation, the final step of the coagulation cascade and determination of plasma viscosity and erythrocyte aggregation. It is both constitutively expressed and inducible during an acute phase reaction. Hemostasis following tissue injury deploys essential plasma procoagulants, which are involved in a blood coagulation cascade leading to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Following vascular injury, Fibrinogen is cleaved by Thrombin to form Fibrin, which is the most abundant component of blood clots. The cleavage products of Fibrinogen regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types.
              More 
              Immunogen
              Recombinant protein

              Key Feature

              Clonality Monoclonal
              Isotype IgG2a
              Host Species Mouse
              Tested Applications

              WBICCIHCFC

               
              WB:1:500-1:1,000
              ICC:1:100-1:500
              IHC:1:100-1:500
              FC:1:100-1:200
              More 
              Species Reactivity

              Human

              Concentration 2 mg/mL.

              Target Information

              Alternative Names
              fggy antibody FGGY carbohydrate kinase domain containing antibody FGGY carbohydrate kinase domain-containing protein antibody FGGY_HUMAN antibody FLJ10986 antibody MGC94804 antibody OTTHUMP00000010078 antibody OTTHUMP00000010081 antibody OTTHUMP00000010082 antibody OTTHUMP00000202071 antibody RP11-242B9.1 antibody
              More 
              Molecular Weight(MW) 52 kDa
              Cellular Localization Secreted.

              Database Links

              SwissProt ID P02679

              Application

              • Application

                Fig1: Western blot analysis of FGG on human FGG recombinant protein using anti-FGG antibody at 1/1,000 dilution.

              • Application

                Fig2: ICC staining FGG (green) and actin filaments (red) in 3T3-L1 cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

              • Application

                Fig3: Immunohistochemical analysis of paraffin-embedded human cerebellum tissue using anti-FGG antibody. Counter stained with hematoxylin.

              • Application

                Fig4: Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-FGG antibody. Counter stained with hematoxylin.

              • Application

                Fig5: Flow cytometric analysis of HepG2 cells with FGG antibody at 1/100 dilution (blue) compared with an unlabelled control (cells without incubation with primary antibody; red).

              Positive Control Human FGG recombinant protein, 3T3-L1, human cerebellum tissue, human liver cancer tissue, HepG2.
              Application Notes
              WB:1:500-1:1,000
              ICC:1:100-1:500
              IHC:1:100-1:500
              FC:1:100-1:200
              More 

              Additional Information

              Form Liquid
              Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
              Storage Buffer 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.

              原創作者:上海篤瑪生物科技有限公司

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