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              技術文章

              Rabbit anti-FGG polyclonal antibody - middle region Catalog Number:OM111725

              點擊次數:25 發布時間:2024/9/19 11:48:58
               

              Product Profile

              Product Name Rabbit anti-FGG polyclonal antibody - middle region
              Antibody Type Primary Antibodies
              Immunogen
              The immunogen for anti-FGG antibody: synthetic peptide directed towards the middle region of human FGG

              Key Feature

              Clonality Polyclonal
              Isotype IgG
              Host Species Rabbit
              Tested Applications

              WB

               
              WB:1:500~1:2000
              Notes:Optimal dilutions/concentrations should be determined by the researcher.
              Species Reactivity

              BovineDogHorseHumanMousePigRabbitZebra Fish

              Concentration 1 mg/ml
              Purification Protein A

              Target Information

              Gene Symbol FGG
              Gene Synonyms
              -
              Gene Full Name Fibrinogen gamma chain
              Gene Summary
              FGG is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in its gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia.The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.
              More 
              Molecular Weight(MW) 46kDa
              Sequence 437 amino acids

              Database Links

              Entrez Gene 2266
              SwissProt ID Q53Y18
              Protein Accession NP_000500

              Application

              • Western blot

                2.5ug/ml
                Positive Control: Human Live

              Application Notes
              WB:1:500~1:2000
              Notes:Optimal dilutions/concentrations should be determined by the researcher.

              Additional Information

              Form Liquid
              Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
              Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

              原創作者:上海篤瑪生物科技有限公司

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