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              技術文章

              FGG Antibody Catalog Number:OM278837

              點擊次數:24 發布時間:2024/9/19 11:48:14
               

              Product Profile

              Product Name FGG Antibody
              Antibody Type Primary Antibodies
              Product description
              FGG is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in its gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia.The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.1) Uitte (2006) J. Thromb. Haemost. 4 (2), 474-476.
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              Immunogen
              Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FGG.

              Key Feature

              Clonality Polyclonal
              Host Species Rabbit
              Tested Applications

              ELISAWB

               
              FGG antibody can be used for detection of FGG by ELISA at 1:312500. FGG antibody can be used for detection of FGG by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
              Species Reactivity

              DogHumanMouseRat

              Concentration 1 mg/ml
              Purification Protein A

              Target Information

              Gene Symbol FGG
              Alternative Names
              FGG
              Molecular Weight(MW) 46 kDa, 52 kDa

              Database Links

              Entrez Gene 2266
              Protein Accession NP_000500

              Application

              • Application

                Antibody used in WB on Human Liver at 2.5 ug/ml.

              Positive Control 1) Cat. No. XBL-10409 - Fetal Liver Tissue Lysate
              Application Notes
              FGG antibody can be used for detection of FGG by ELISA at 1:312500. FGG antibody can be used for detection of FGG by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:

              Additional Information

              Form Liquid
              Storage Instructions For short periods of storage (days) store at 4˚C. For longer periods of storage, store FGG antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
              Storage Buffer IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt

              原創作者:上海篤瑪生物科技有限公司

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