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              技術文章

              Phospho-Gab1-Y659 Antibody Catalog Number:OM217327

              點擊次數:24 發布時間:2024/9/14 13:43:12
               

              Product Profile

              Product Name Phospho-Gab1-Y659 Antibody
              Antibody Type Primary Antibodies

              Key Feature

              Clonality Polyclonal
              Isotype Ig
              Host Species Rabbit
              Tested Applications

              DB

               
              DB~~1:100~500:
              Species Reactivity

              Human

              Concentration 1 mg/ml
              Purification  

              Target Information

              Alternative Names
              GAB1
              GRB2-associated-binding protein 1
              GRB2-associated binder 1
              Growth factor receptor bound protein 2-associated protein 1
              More 
              Molecular Weight(MW) 76616 Da
              Function
              Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR)
              Tissue Specificity This Phospho-Gab1-Y659 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide between 645~675 amino acids surrounding Y659 of human Gab1.

              Database Links

              Entrez Gene 2549

              Application

              • Application

                Dot blot analysis of Phospho-Gab1-Y659 polyclonal antibody (Cat. AP3302b) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentration were 0.5ug per ml.

              Application Notes
              DB~~1:100~500:

              Additional Information

              Form Liquid
              Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
              Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is first purified by protein A affinity chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with peptides. The antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
               

              原創作者:上海篤瑪生物科技有限公司

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