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              技術文章

              GAB1 antibody Catalog Number:OM253807

              點擊次數:26 發布時間:2024/9/14 13:39:58
               

              Product Profile

              Product Name GAB1 antibody
              Antibody Type Primary Antibodies
              Product description
              Rabbit Polyclonal antibody to GAB1 (GRB2-associated-binding protein 1)The protein encoded by this gene is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
              More 
              Immunogen
              Recombinant protein encompassing a sequence within the center region of human GAB1. The exact sequence is proprietary.

              Key Feature

              Clonality Polyclonal
              Isotype IgG
              Host Species Rabbit
              Tested Applications

              IHC-PWB

               
              *Optimal dilutions/concentrations should be determined by the researcher. :
              Species Reactivity

              HumanMouse

              Predicted Reactivity Rat, Rhesus Monkey, BovineRat (86%), Rhesus Monkey (100%), Bovine (93%)
              Concentration 1 mg/ml (Please refer to the vial label for the specific concentration)
              Purification Affinity purified

              Target Information

              Gene Synonyms
              GAB1 antibody
              GRB2-associated binder 1 antibody
              growth factor receptor bound protein 2-associated protein 1 antibody
              GRB2-associated-binding protein 1 antibody
              GRB2-associated binding protein 1 antibody
              More 
              Molecular Weight(MW) 77 kDa (note) (2)

              Application

              • Application

                Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using GAB1 antibody at 1:500 dilution.

              • Application

                Sample (30 µg of whole cell lysate) A: JC B: BCL-1 7.5% SDS PAGE diluted at 1:2000 The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

              • Application

                Sample (30 µg of whole cell lysate) A: HCT116 B: MCF-7 7.5% SDS PAGE diluted at 1:2000 The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

              Positive Control HCT116 , MCF-7 , JC , BCL-1 , *C2C12
              Application Notes
              *Optimal dilutions/concentrations should be determined by the researcher. :

              Additional Information

              Form Liquid
              Storage Instructions Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
              Storage Buffer 1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

              原創作者:上海篤瑪生物科技有限公司

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