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              技術文章

              eIF4B Antibody Catalog Number:OM277786

              點擊次數:19 發布時間:2024/9/13 13:39:43
               

              Product Profile

              Product Name eIF4B Antibody
              Antibody Type Primary Antibodies
              Product description
              Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.1) Gingras, A. C. et al. (2001) Genes Dev. 15, 807-826. Duncan, R. and Hershey, J. W. (1985) J. Biol. Chem. 260, 5493-5497. Duncan, R. F. and Hershey, J. W. (1989) J. Cell Biol. 109, 1467-1481.
              More 
              Immunogen
              eIF4B (Ab-422) antibody was raised against a peptide sequence around aa.420~424 (T-G-S-E-S) derived from Human eIF4B.

              Key Feature

              Clonality Polyclonal
              Host Species Rabbit
              Tested Applications

              IHCWB

               
              Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:
              Species Reactivity

              Human

              Concentration 1 mg/ml
              Purification Affinity purified

              Target Information

              Gene Symbol EIF4B
              Alternative Names
              EIF-4B
              PRO1843
              PKB
              RAC
              More 
              Molecular Weight(MW) 80 kDa
              Tissue Specificity This antibody detects endogenous level of total eIF4B protein.

              Database Links

              Entrez Gene 1975
              Protein Accession NP_001408.2

              Application

              • Application

                Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using eIF4B (Ab-422).

              • Application

                Western blot analysis of lysed extracts from 3T3 and HL60 cells using eIF4B (Ab-422).

              Application Notes
              Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:

              Additional Information

              Form Liquid
              Storage Instructions Store antibody at -20˚C for up to one year.
              Storage Buffer Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

              原創作者:上海篤瑪生物科技有限公司

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