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              技術文章

              Mapk8 Antibody Catalog Number:OM285161

              點擊次數:30 發布時間:2024/9/12 15:13:15
               

              Product Profile

              Product Name Mapk8 Antibody
              Antibody Type Primary Antibodies
              Product description
              Mapk8 responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as JUN, JDP2 and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells. Phosphorylates heat shock factor protein 4 (HSF4) (By similarity).1) Sherrin, T., et al. J. Neurosci. 30(40):13348-13361(2010)
              More 
              Immunogen
              This Mouse Mapk8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-268 amino acids from the Central region of mouse Mapk8.

              Key Feature

              Clonality Polyclonal
              Isotype Ig
              Host Species Rabbit
              Tested Applications

              WB

               
              For WB starting dilution is: 1:1000:
              Species Reactivity

              Human

              Concentration 1 mg/ml
              Purification Affinity purified

              Target Information

              Gene Symbol Mapk8
              Alternative Names
              Mitogen-activated protein kinase 8
              MAP kinase 8
              MAPK 8
              Stress-activated protein kinase JNK1
              c-Jun N-terminal kinase 1
              Mapk8
              Jnk1
              Prkm8
              More 
              Molecular Weight(MW) 44 kDa
              Sequence Similarities Predicted species reactivity based on immunogen sequence: Rat

              Database Links

              Entrez Gene 26419
              Protein Accession Q91Y86

              Application

              • Application

                Western blot analysis in MCF-7 cell line lysates (35ug/lane).

              Application Notes
              For WB starting dilution is: 1:1000:

              Additional Information

              Form Liquid
              Storage Instructions Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
              Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.

              原創作者:上海篤瑪生物科技有限公司

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