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              聯系人:楊燕燕

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              技術文章

              PPM1A antibody Catalog Number:OM269349

              點擊次數:30 發布時間:2024/9/12 13:24:05
               

              Product Profile

              Product Name PPM1A antibody
              Antibody Type Primary Antibodies
              Product description
              Mouse monoclonal [p6c7] to PPM1APPM1A is a Mn2+- or Mg2+-dependent protein serine/threonine phosphatase that inhibits the human stress-responsive p38 and JNK MAPK pathways and regulates cellular stress response in eukaryotes. The PPM (metal-dependent protein phosphatase) family of Ser/Thr protein phosphatases have recently been shown to down-regulate the stress response pathways in eukaryotes. Within the stress pathway, key signaling kinases, which are activated by protein phosphorylation, have been proposed as the in vivo substrates of PP2C, the prototypical member of the PPM family.
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              Immunogen
              Recombinant full length protein (Human).

              Key Feature

              Clonality Monoclonal
              Isotype IgG2
              Clone Number p6c7
              Host Species Mouse
              Tested Applications

              ELISAWB

               
              ELISA: Use at an assay dependent dilution. WB: Use at a dilution of 1/250 - 1/1000. Predicted molecular weight: 42 kDa. Optimal dilutions/concentrations should be determined by the end user.:
              Species Reactivity

              HumanMouse

              Concentration 1 mg/ml
              Purification Protein G

              Target Information

              Gene Synonyms
              EC 3.1.3.16 MGC9201 Mpp alpha Protein phosphatase 1A Protein phosphatase 1A magnesium dependent alpha
              Target PPM1A
              Cellular Localization Cylasmic
              Light Chain Type kappa

              Application

              • Application

                Western blot analysis of mouse liver cytosol extract using at a dilution of 1/250. Proteins were visualised using a goat anti-mouse secondary antibody conjugated to HRP and a DAB detection system.

              Application Notes
              ELISA: Use at an assay dependent dilution. WB: Use at a dilution of 1/250 - 1/1000. Predicted molecular weight: 42 kDa. Optimal dilutions/concentrations should be determined by the end user.:

              Additional Information

              Form Liquid
              Storage Instructions Upon receipt - Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
              Storage Buffer Preservative: 0.1% Sodium Azide; Constituents: PBS. pH 7.4
               

              原創作者:上海篤瑪生物科技有限公司

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