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              技術文章

              GluR2 (phospho Ser880) antibody Catalog Number:OM254731

              點擊次數:26 發布時間:2024/9/11 13:50:03
               

              Product Profile

              Product Name GluR2 (phospho Ser880) antibody
              Antibody Type Primary Antibodies
              Product description
              Rabbit polyclonal antibody to GluR2 (phospho Ser880)Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist.
              More 
              Immunogen
              Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser880 conjugated to KLH.

              Key Feature

              Clonality Polyclonal
              Isotype IgG
              Host Species Rabbit
              Tested Applications

              WB

               
              Optimal working dilutions should be determined experimentally by the end user.:
              Species Reactivity

              Rat

              Predicted Reactivity chicken, human, mouse, non-human primate and Zebrafish(100%)
              Concentration 1 mg/ml
              Purification Affinity purified

              Target Information

              Gene Synonyms
              HBGR2
              GluR-K2
              GluRK2
              GRIA2
              GLURB
              GluA2
              GLUR2
              GluR K2
              GluR2-subunit (phospho S880)
              GluR2-subunit (phospho Ser880)
              GluR2-subunit (pS880)
              GluR2-subunit (pSer880)
              GluR2-subunit phospho S880
              GluR2-subunit phospho Ser880
              Phospho GluR2-subunit (S880
              More 
              Target GluR2 (phospho Ser880)
              Molecular Weight(MW) 100 (note)
              Cellular Localization Interaction with CACNG2 promotes cell surface expression.

              Application

              • Application

                 

              • Application

                Western Blot: Glutamate receptor 2 [Phospho-Ser880] Antibody [ - rat brain homogenate showing specific immunolabeling of the ~100k GluR2 protein phosphorylated at Ser880 (control). Immunolabeling is blocked by preadsorption with the phospho-peptide used as antigen (Peptide) but not by the corresponding dephospho-peptide (not shown).

              Application Notes
              Optimal working dilutions should be determined experimentally by the end user.:

              Additional Information

              Form Liquid
              Storage Instructions For long-term storage, aliquot and store at -20 C. Avoid repeated freeze/thaw cycles.
              Storage Buffer 100 µl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.

              原創作者:上海篤瑪生物科技有限公司

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