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              技術文章

              ARHGDIA Antibody (N-term) Catalog Number:OM226834

              點擊次數:36 發布時間:2024/9/10 11:26:46
               

              Product Profile

              Product Name ARHGDIA Antibody (N-term)
              Antibody Type Primary Antibodies

              Key Feature

              Clonality Polyclonal
              Isotype Ig
              Host Species Rabbit
              Tested Applications

              WB

               
              WB~~1:100~500:
              Species Reactivity

              Human

              Concentration 1 mg/ml
              Purification  

              Target Information

              Gene Synonyms
              GDIA1
              Alternative Names
              ARHGDIA
              GDIA1
              Rho GDP-dissociation inhibitor 1
              Rho-GDI alpha
              More 
              Molecular Weight(MW) 23207 Da
              Function
              Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. In glioma cells, inhibits cell migration and invasion by mediating the signals of SEMA5A and PLXNB3 that lead to inactivation of RAC1 (By similarity)
              More 
              Tissue Specificity This ARHGDIA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32~61 amino acids from the N-terminal region of human ARHGDIA.
              Cellular Localization Cylasm.

              Database Links

              Entrez Gene 396

              Application

              • Application

                Western blot analysis of ARHGDIA Antibody (N-term) in A2058, Jurkat, Ramos cell line and mouse lung tissue lysates (35ug/lane). ARHGDIA (arrow) was detected using the purified Pab.

              • Application

                Western blot analysis of ARHGDIA (arrow) using rabbit polyclonal ARHGDIA Antibody (N-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the ARHGDIA gene.

              Application Notes
              WB~~1:100~500:

              Additional Information

              Form Liquid
              Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
              Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

              原創作者:上海篤瑪生物科技有限公司

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