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              技術文章

              CD55 antibody Catalog Number:OM245671

              點擊次數:26 發布時間:2024/9/5 13:47:22
               

              Product Profile

              Product Name CD55 antibody
              Antibody Type Primary Antibodies
              Product description
              Rabbit Polyclonal antibody to CD55 (CD55 molecule, decay accelerating factor for complement (Cromer blood group))This gene encodes a protein involved in the regulation of the complement cascade. The encoded glycoprotein is also known as the decay-accelerating factor (DAF); binding of DAF to complement proteins accelerates their decay, disrupting the cascade and preventing damage to host cells. Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM). Two alternatively spliced transcripts encoding different proteins have been identified. The predominant transcript encodes a membrane-bound protein expressed on cells exposed to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels. Additional, alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq]
              More 
              Immunogen
              Recombinant protein encompassing a sequence within the center region of human CD55. The exact sequence is proprietary.

              Key Feature

              Clonality Polyclonal
              Isotype IgG
              Host Species Rabbit
              Tested Applications

              ICC/IFWB

               
              *Optimal dilutions/concentrations should be determined by the researcher. :
              Species Reactivity

              Human

              Concentration 1 mg/ml
              Purification Affinity purified

              Target Information

              Gene Synonyms
              CR antibody
              CROM antibody
              DAF antibody
              TC antibody
              CD55 antibody
              CD55 antigen antibody
              decay accelerating factor for complement antibody
              complement decay-accelerating factor antibody
              "CD55 molecule
              decay accelerating factor for complement (Cromer
              More 
              Molecular Weight(MW) 41 kDa (note) (6)
              Cellular Localization Isoform 1: Membrane , Isoform 2: Cell membrane , GPI-anchor

              Application

              • Application

                Sample (30 ug of whole cell lysate) A: A431 10% SDS PAGE diluted at 1:1000

              • Application

                Immunofluorescence analysis of methanol-fixed HeLa, using CD55 antibody at 1:200 dilution.

              Positive Control A431 , H1299 , HeLa , HepG2 , Molt-4
              Application Notes
              *Optimal dilutions/concentrations should be determined by the researcher. :

              Additional Information

              Form Liquid
              Storage Instructions Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
              Storage Buffer 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

              原創作者:上海篤瑪生物科技有限公司

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