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              技術文章

              CD59 antibody Catalog Number:OM245691

              點擊次數:34 發布時間:2024/9/4 15:05:45
               

              Product Profile

              Product Name CD59 antibody
              Antibody Type Primary Antibodies
              Product description
              Rabbit polyclonal antibody to CD59This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
              More 
              Immunogen
              Recombinant protein of human CD59

              Key Feature

              Clonality Polyclonal
              Isotype IgG
              Host Species Rabbit
              Tested Applications

              IHC-PWB

               
              WB: 1:500 - 1:2000. IHC: 1:50 - 1:200.:
              Species Reactivity

              Human

              Concentration 1 mg/ml
              Purification Affinity purified

              Target Information

              Gene Synonyms
              MIN1
              1F5
              EL32
              MIRL
              MAC-IP
              HRF-20
              G344
              EJ30
              MIC11
              MIN3
              MEM43
              EJ16
              MACIF
              MSK21
              MIN2
              p18-20
              CD59 molecule
              complement regulatory protein
              16.3A5
              HRF20
              More 
              Target CD59
              Molecular Weight(MW) 19 kDa (note)

              Application

              • Application

                WB analysis of HeLa lysate using CD59 antibody.

              Application Notes
              WB: 1:500 - 1:2000. IHC: 1:50 - 1:200.:

              Additional Information

              Form Liquid
              Storage Instructions Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles.
              Storage Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

              原創作者:上海篤瑪生物科技有限公司

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