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              技術文章

              PDE1B antibody Catalog Number:OM267836

              點擊次數:29 發布時間:2024/9/3 14:24:43
               

              Product Profile

              Product Name PDE1B antibody
              Antibody Type Primary Antibodies
              Product description
              Rabbit Polyclonal antibody to PDE1BThe protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
              More 
              Immunogen
              Recombinant protein of human PDE1B

              Key Feature

              Clonality Polyclonal
              Isotype IgG
              Host Species Rabbit
              Tested Applications

              ICC/IFIHC-PWB

               
              WB: 1:500 - 1:2000. IHC: 1:50 - 1:200. IF: 1:50 - 1:200:
              Species Reactivity

              HumanMouseRat

              Concentration 1 mg/ml
              Purification Affinity purified

              Target Information

              Gene Synonyms
              PDE1B1
              phosphodiesterase 1B
              calmodulin-dependent
              PDES1B
              More 
              Target PDE1B
              Molecular Weight(MW) 61 kDa (note)

              Application

              • Application

                WB analysis of extracts from various cells using PDE1B antibody.

              • Application

                IHC-P analysis of human kidney cancer using PDE1B antibody at a dilution of 1:200.

              • Application

                IHC-P analysis of human lung cancer using PDE1B antibody at a dilution of 1:200.

              • Application

                ICC/IF analysis of MCF7 cells using PDE1B antibody (green) and DAPI (blue).

              • Application

                ICC/IF analysis of U2OS cells using PDE1B antibody (green) and DAPI (blue).

              Application Notes
              WB: 1:500 - 1:2000. IHC: 1:50 - 1:200. IF: 1:50 - 1:200:

              Additional Information

              Form Liquid
              Storage Instructions Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles.
              Storage Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

              原創作者:上海篤瑪生物科技有限公司

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