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              技術文章

              PDE1B antibody Catalog Number:OM267840

              點擊次數:26 發布時間:2024/9/3 14:17:39
               

              Product Profile

              Product Name PDE1B antibody
              Antibody Type Primary Antibodies
              Product description
              Mouse Monoclonal Antibody [5C4A3] to PDE1BThe protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
              More 
              Immunogen
              The immunogen corresponding to a region within amino acids 370 and 536 of human PDE1B expressed in E. Coli.

              Key Feature

              Clonality Monoclonal
              Isotype IgG1
              Clone Number 5C4A3
              Host Species Mouse
              Tested Applications

              ELISAFACSIHCIHC-PWB

               
              ELISA: 1/10000.:
              Species Reactivity

              Human

              Concentration 1 mg/ml
              Purification  

              Target Information

              Gene Synonyms
              PDES1B
              PDE1B1
              Target PDE1B
              Molecular Weight(MW) 61.4 kDa (note)

              Application

              • Application

                ELISA analysis of control antigen and antigen using PDE1B antibody [5C4A3].

              • Application

                FACS analysis of A549 cells using PDE1B antibody [5C4A3] (green) or a negative control (red).

              • Application

                IHC-P analysis of ovarian cancer tissues using PDE1B antibody [5C4A3].

              • Application

                IHC-P analysis of rectum cancer tissues using PDE1B antibody [5C4A3].

              • Application

                WB analysis of lysates from (1) untransfected and (2) PDE1B (a.a. 370-536)-hIgGFc transfected HEK293 cells using PDE1B antibody [5C4A3].

              • Application

                WB analysis of human PDE1B recombinant protein using PDE1B antibody [5C4A3].

              Application Notes
              ELISA: 1/10000.:

              Additional Information

              Form Liquid
              Storage Instructions 4°C; -20°C for long term storage
              Storage Buffer Ascitic fluid containing 0.03% sodium azide.
               

              原創作者:上海篤瑪生物科技有限公司

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