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              技術文章

              WHSC2 Antibody (Center) Catalog Number:OM224700

              點擊次數:20 發布時間:2024/9/2 14:06:25
               

              Product Profile

              Product Name WHSC2 Antibody (Center)
              Antibody Type Primary Antibodies

              Key Feature

              Clonality Polyclonal
              Isotype Ig
              Host Species Rabbit
              Tested Applications

              WB

               
              WB~~1:100~500:
              Species Reactivity

              Human

              Concentration 1 mg/ml
              Purification  

              Target Information

              Gene Synonyms
              WHSC2
              Alternative Names
              WHSC2
              NELFA
              Negative elongation factor A
              Wolf-Hirschhorn syndrome candidate 2 protein
              More 
              Molecular Weight(MW) 57277 Da
              Function
              Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. Probably required to interact with the RNA polymerase II complex
              More 
              Tissue Specificity Ubiquitous. Expressed in heart, brain, placenta, liver, skeletal muscle, kidney and pancreas. Expressed at lower level in adult lung. Expressed in fetal brain, lung, liver and kidney
              Cellular Localization Nucleus.

              Database Links

              Entrez Gene 7469
              Nucleotide Accession NP_005654.3

              Application

              • Application

                WHSC2 Antibody (Center) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the WHSC2 antibody detected the WHSC2 protein (arrow).

              Application Notes
              WB~~1:100~500:

              Additional Information

              Form Liquid
              Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
              Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

              原創作者:上海篤瑪生物科技有限公司

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