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              技術文章

              ITGB4 (phospho Tyr1510) Antibody Catalog Number:OM282419

              點擊次數:32 發布時間:2024/8/29 15:07:20
                

              Product Profile

              Product Name ITGB4 (phospho Tyr1510) Antibody
              Antibody Type Primary Antibodies
              Product description
              Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility.1) Suzuki S., EMBO J. 9:757-763(1990).
              Immunogen
              ITGB4 (phospho Tyr1510) antibody was raised against a peptide sequence around phosphorylation site of tyrosine1510 (R-D-Y (p)-S-T) derived from Human ITGB4 .

              Key Feature

              Clonality Polyclonal
              Isotype IgG
              Host Species Rabbit
              Tested Applications

              IHC

               
              Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:
              Species Reactivity

              MouseRat

              Concentration 1 mg/ml
              Purification Affinity purified

              Target Information

              Gene Symbol ITGB4
              Alternative Names
              GP150
              ITB4
              CD104 antigen
              Molecular Weight(MW) 202 kDa
              Tissue Specificity The antibody detects endogenous levels of ITGB4 only when phosphorylated at tyrosine 1510.

              Database Links

              Entrez Gene 3691
              Protein Accession NP_000204.3

              Application

              • Application

                Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using ITGB4 (Phospho-Tyr1510) antibody (left) or the same antibody preincubated with blocking peptide (right).

              Application Notes
              Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:

              Additional Information

              Form Liquid
              Storage Instructions Store antibody at -20˚C for up to one year.
              Storage Buffer Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

              原創作者:上海篤瑪生物科技有限公司

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