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              • 注冊資金:人民幣萬

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              技術文章

              FGF4 antibody Catalog Number:OM252983

              點擊次數:19 發布時間:2024/8/27 11:52:03
               

              Product Profile

              Product Name FGF4 antibody
              Antibody Type Primary Antibodies
              Product description
              Rabbit polyclonal antibody to FGF4Fibroblast growth factor 4 (FGF4) is a member of the fibroblast growth factor (FGF) family that possess broad mitogenic and cell survival activities and play key roles in growth and survival of stem cells during embryogenesis, tissue regeneration, and carcinogenesis. FGF4 was identified by its strong oncogenic transforming activity and is a potent angiogenic factor, expressed in several highly vascularized tumors and also in adult mouse testis, intestine, and brain. Studies on the mouse homolog suggests a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. Furthermore, FGF4 regulates neural progenitor cell proliferation and neuronal differentiation. Recent studies show a growth-promoting role for FGF4 in human embryonic stem cells and a putative feedback inhibition mechanism by a novel FGF4 splice isoform that may serve to promote differentiation at a later stages of development.
              More 

              Key Feature

              Clonality Polyclonal
              Host Species Rabbit
              Tested Applications

              ELISAICC/IFWB

               
              ICC/IF:1:200~1:500
              WB:1:500~1:2000
              Notes:Optimal dilutions/concentrations should be determined by the researcher.
              Species Reactivity

              HumanMouse

              Concentration 1 mg/ml
              Purification Affinity purified

              Target Information

              Gene Synonyms
              Fibroblast growth factor 4
              HBGF-4
              FGF4
              Heparin secretorytransforming protein
              Fibroblast growth factor4
              HST1
              HST
              Transforming protein KS3
              HBGF4
              Kaposi sarcoma oncogene
              HST-1
              Heparin secretory-transforming protein
              HST 1
              HBGF 4
              More 
              Target FGF4
              Tissue Specificity This antibody is specific for FGF4

              Application

              • Application

                Immunofluorescence of FGF4 in 3T3 cells with FGF4 antibody at 2.5 ug/mL.

              • Application

                Western blot analysis of FGF4 in NIH 3T3 cell lysate with FGF4 antibody at (A) 0.5 and (B) 1 ug/ml.

              • Application

                Immunocytochemistry of FGF4 in 3T3 cells with FGF4 antibody at 2.5 ug/ml.

              Positive Control Blocking Peptide: Cat.No. GTX85040-PEP - FGF4 Peptide Lysates: Cat. No. GTX27901 - 3T3 (NIH) Cell Lysate
              Application Notes
              ICC/IF:1:200~1:500
              WB:1:500~1:2000
              Notes:Optimal dilutions/concentrations should be determined by the researcher.

              Additional Information

              Form Liquid
              Storage Instructions Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
              Storage Buffer Antibody is supplied in PBS containing 0.02% sodium azide

              原創作者:上海篤瑪生物科技有限公司

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