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              技術文章

              FGF4 [D5-7] Catalog Number:OM627599

              點擊次數:29 發布時間:2024/8/26 14:33:30
                

              Product Profile

              Product Name FGF4 [D5-7]
              Antibody Type Primary Antibodies
              Product description
              Fibroblast growth factor-1 (FGF-1), also designated acidic FGF, and fibroblast growth factor-2 (FGF-2), also designated basic FGF, are members of a family of growth factors that stimulate proliferation of cells of mesenchymal, epithe-lial and neuroectodermal origin. Additional members of the FGF family include the oncogenes FGF-3 (Int2) and FGF-4 (hst/Kaposi), FGF-5, FGF-6, FGF-7 (KGF), FGF-8 (AIGF), FGF-9 (GAF) and FGF-10-FGF-23. Members of the FGF family share 30-55% amino acid sequence identity and similar gene structure, and are capable of transforming cultured cells when overexpressed in transfected cells. Cellular receptors for FGFs are members of a second multigene family including four tyrosine kinases, designated Flg (FGFR-1), Bek (FGFR-L), TKF and FGFR-3.
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              Immunogen
              Recombinant protein

              Key Feature

              Clonality Monoclonal
              Isotype IgG1
              Host Species Mouse
              Tested Applications

              WBFC

               
              WB:1:250~1:1000
              FC:1:100~1:200
              Notes:Optimal dilutions/concentrations should be determined by the researcher.
              Species Reactivity

              Human

              Concentration 2 mg/mL.

              Target Information

              Alternative Names
              FGF-4 antibody Fgf4 antibody FGF4_HUMAN antibody Fibroblast growth factor 4 antibody fibroblast growth factor 4 splice isoform antibody HBGF-4 antibody HBGF4 antibody Heparin secretory-transforming protein 1 antibody Heparin-binding growth factor 4 antibody Hst antibody HST-1 antibody HST1 antibody HSTF-1 antibody HSTF1 antibody Human stomach cancer transforming factor from FGF related oncogene antibody K FGF antibody Kaposi Sarcoma Oncogene antibody KFGF antibody KS3 antibody Oncogene HST antibody Transforming protein KS3 antibody
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              Molecular Weight(MW) 22 kDa
              Cellular Localization Secreted.

              Database Links

              SwissProt ID P08620

              Application

              • Application

                Fig1: Western blot analysis of FGF4 on human FGF4 recombinant protein using anti-FGF4 antibody at 1/1,000 dilution.

              • Application

                Fig2: Western blot analysis of FGF4 on HEK293 (1) and FGF4-hIgGFc transfected HEK293 (2) cell lysate using anti-FGF4 antibody at 1/1,000 dilution.

              • Application

                Fig3: Flow cytometric analysis of NIH/3T3 cells with FGF4 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).

              Positive Control Human FGF4 recombinant protein, FGF4-hIgGFc transfected HEK293 cell lysate, NIH/3T3.
              Application Notes
              WB:1:250~1:1000
              FC:1:100~1:200
              Notes:Optimal dilutions/concentrations should be determined by the researcher.

              Additional Information

              Form Liquid
              Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
              Storage Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

              原創作者:上海篤瑪生物科技有限公司

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