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              技術文章

              BRCA1 antibody Catalog Number:OM241917

              點擊次數:44 發布時間:2024/8/23 13:56:28
               

              Product Profile

              Product Name BRCA1 antibody
              Antibody Type Primary Antibodies
              Product description
              Mouse monoclonal [GLK-2] to BRCA1GTX17251 stains 94% of ovarian carcinomas with a mutation in exon 11. However, staining is absent in 100% of tumors with mutations other than exon 11.
              Immunogen
              Synthetic peptide: LDSVALYQCQELDTYLIPQIPHSHY, corresponding to C terminal amino acids 1839-1863 of Human BRCA1.

              Key Feature

              Clonality Monoclonal
              Isotype IgM
              Clone Number GLK-2
              Host Species Mouse
              Tested Applications

              IHC-P

               
              IHC-P: 1/15 - 1/50 in an ABC method. An incubation period of 30-60 minutes at room temperature is recommended. Perform heat mediated antigen retrieval with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Optimal dilutions/concentrations should be determined by the end user.:
              Species Reactivity

              HumanDogMonkeyChimpanzeeGorillaBovine

              Concentration 1 mg/ml

              Target Information

              Gene Synonyms
              113705
              RNF53
              BRCA1
              BRCAI
              672
              PSCP
              BRCC1
              P38398
              IRIS
              More 
              Target BRCA1
              Cellular Localization Nuclear

              Application

              Positive Control Ovarian carcinoma
              Application Notes
              IHC-P: 1/15 - 1/50 in an ABC method. An incubation period of 30-60 minutes at room temperature is recommended. Perform heat mediated antigen retrieval with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Optimal dilutions/concentrations should be determined by the end user.:

              Additional Information

              Form Liquid
              Storage Instructions Keep as concentrated solution, aliquot and store at 4°C. Do not freeze.
              Storage Buffer Preservative: Sodium Azide. Constituents: Tissue culture supernatant

              原創作者:上海篤瑪生物科技有限公司

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