產品展示
優質供應
詳細內容
艾美捷LKT Labs AB-680#A040068參數說明:
Cas No.:2105904-82-1
純度:≥98%
公式:C20H24氯氟乙烯4O9P2
配方重量:580.83
IUPAC名稱:[[(2R,3S,4R,5R)-5-[6-氯-4-[[(1S)-1-(2-氟苯基)乙基]氨基]吡唑并[3,4-b]吡啶-1-基]-3,4-二羥基氧代-2-基]甲氧基羥基磷酸基]甲基膦酸
同義詞:AB680, 奎姆利盧司他
外觀:類白色粉末
儲存溫度:-20°C
LKT Labs-AB-680文獻引用:
Faraoni E, Strickland L, O’Brien B, et al. Radiofrequency ablation in combination with CD73 inhibitor AB680 reduces tumor growth and enhances anti-tumor immunity in a syngeneic model of pancreatic ductal adenocarcinoma. Front Oncol. 2022 Sep 6;12:995027. PMID: 36147911
Noh J, Lee I, Han N, et al. Additive effect of CD73 inhibitor in colorectal cancer treatment with CDK4/6 inhibitor through regulation of PD-L1. Cell Mol Gastroenterol Hepatol. 2022;14(4):769-788. PMID: 35843546
Kim M, Min Y, Jang J, et al. Single-cell RNA sequencing reveals distinct cellular factors for response to immunotherapy targeting CD73 and PD-1 in colorectal cancer. J Immunother Cancer. 2021 Jul;9(7):e002503. PMID: 34253638
LKT Laboratories(LKT Labs)注于防癌抗癌特殊化學品研究和開發域。主要包括:癌癥藥物、藥物發現試劑盒、天然產物、廣泛的生命科學研究試劑、定制合成等。同時注研究用小分子的合成,純化和分離。主要應用于癌癥和神經科學等,包括蛋白激酶抑制劑、離子通道調節劑和激活劑等。艾美捷科技是LKT Labs的中國代理商,為科研工作者提供優質的產品與服務。
來源:https://www.amyjet.com/news/LKT-Laboratories-new.shtml