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艾美捷LKT Labs-雙葉堿#B3211參數說明:
Cas No.:485-49-4
純度:≥98%
公式:C20H17NO6
配方重量:367.35
化學名稱:6R-6-甲基-5,6-二氫-7H-[8,5]二氧雜環戊二烯并[1,3-g]異喹啉-4-基]-5H-呋喃[5,6-g][3,4]苯并二氧雜環戊烯-1-酮
IUPAC名稱:6R-6-甲基-5,6-二氫-7H-[8,5]二氧戊二醇[1, 3-g]異喹啉-4-基]-5H-呋喃[5,6-g][3,4]苯并二氧雜環戊烯-1-酮
同義詞:d-二葫蘆堿
外觀:白色至類白色粉末
LKT Labs-雙葉堿文獻引用:
Dela Peña IJ, Lee HL, Yoon SY, et al. The ethanol extract of Cirsium japonicum increased chloride ion influx through stimulating GABA(A) receptor in human neuroblastoma cells and exhibited anxiolytic-like effects in mice. Drug Discov Ther. 2013 Feb;7(1):18-23. PMID: 23524939.
Torkaman-Boutorabi A, Soltani S, Oryan S, et al. Involvement of the dorsal hippocampal GABA-A receptors in histamine-induced facilitation of memory in the Morris water maze. Pharmacol Biochem Behav. 2013 Apr;105:142-50. PMID: 23438692.
Ionov ID, Roslavtseva LA. Coadministration of bicuculline and NMDA induces paraplegia in the rat. Brain Res. 2012 Apr 27;1451:27-33. PMID: 22445063
Ji G, Neugebauer V. Pain-related deactivation of medial prefrontal cortical neurons involves mGluR1 and GABA(A) receptors. J Neurophysiol. 2011 Nov;106(5):2642-52. PMID: 21880942.
Costa LG, Doctor SV, Murphy SD. Antinociceptive and hypothermic effects of trimethyltin. Life Sci. 1982 Sep 13;31(11):1093-102. PMID: 6890611.
Heyer EJ, Nowak LM, Macdonald RL. Membrane depolarization and prolongation of calcium-dependent action potentials of mouse neurons in cell culture by two convulsants: bicuculline and penicillin. Brain Res. 1982 Jan 28;232(1):41-56. PMID: 7055710.
LKT Laboratories(LKT Labs)注于防癌抗癌特殊化學品研究和開發域。主要包括:癌癥藥物、藥物發現試劑盒、天然產物、廣泛的生命科學研究試劑、定制合成等。同時注研究用小分子的合成,純化和分離。主要應用于癌癥和神經科學等,包括蛋白激酶抑制劑、離子通道調節劑和激活劑等。艾美捷科技是LKT Labs的中國代理商,為科研工作者提供優質的產品與服務。