脂肪酸結合蛋白6（FABP6）是細胞內脂質結合蛋白（iLBP）家族的一員，在膽汁酸穩態中發揮作用。它由10條反平行的β鏈組成，形成含有脂質結合位點的β桶，主要在回腸的腸上皮細胞中表達，FABP6結合膽汁酸和脂肪酸，并與回腸膽汁酸轉運蛋白相互作用，以幫助膽汁酸吸收，促進膽汁酸的細胞內運輸，大腸癌患者血清FABP6水平升高，手術切除癌組織后降低。FABP6T79M與肥胖個體2型糖尿病風險降低相關。

Cayman ChemicalFABP6兔單克隆抗體（克隆201）可用于流式細胞術（FC），免疫細胞化學（ICC）和免疫熒光（IF）應用。

Cayman Chemical艾美捷FABP6兔單克隆抗體技術參數：

同義詞：脂肪酸結合蛋白6、腸膽汁酸結合蛋白

免疫原：重組人FABP6

配方：50或100µl蛋白A親和純化單克隆抗體

宿主：兔子

同種型：IgG抗體

應用：FC，ICC，IF

存儲：-80℃

穩定性：≥1年

Cayman Chemical艾美捷FABP6兔單克隆抗體相關文獻：

1. Smathers, R.L., ａnd Petersen, D.R. The human fatty acid-binding protein family: Evolutionary divergences ａnd functions. Hum. Genomics 5(3), 170-191 (2011).

2. Hendrick, A.G., Müller, I., Willems, H., et al. Identification ａnd investigation of novel binding fragments in the fatty acid binding protein 6 (FABP6). J. Med. Chem. 59(17), 8094-8102 (2016).

3. Storch, J., ａnd McDermott, L. Structural ａnd functional analysis of fatty acid-binding proteins. J. Lipid Res. 50 Suppl(Suppl), S126-S131 (2009).

4. Kim, K., Cistola, D.P., ａnd Frieden, C. Intestinal fatty acid-binding protein: The structure ａnd stability of a helix-less variant. Biochemistry 35(23), 7553-7558 (1996).

5. Habib, S.M., Zwicker, B.L., Wykes, L., et al. Sexually dimorphic response of mice to the Western-style diet caused by deficiency of fatty acid binding protein 6 (Fabp6). Physiol. Rep. 9(3), e14733 (2021).

6. Zhang, Y., Zhao, X., Deng, L., et al. High expression of FABP4 ａnd FABP6 in patients with colorectal cancer. World J. Surg. Oncol. 17(1), 171 (2019).

7. Fisher, E., Grallert, H., Klapper, M., et al. Evidence for the Thr79Met polymorphism of the ileal fatty acid binding protein (FABP6) to be associated with type 2 diabetes in obese individuals. Mol. Genet. Metab. 98(4), 400-405 (2009).

Cayman Chemical涉及癌癥、腫瘤、氧化損傷、凋亡、氧化性損傷、代謝、內分泌學等多種研究域。艾美捷科技是Cayman Chemical的中國代理商，為科研工作者提供優質的產品與服務。

來源：https://www.amyjet.com/brand/cayman-china-distributor.shtml